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	<title>Comments for Code for Life</title>
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	<link>http://sciblogs.co.nz/code-for-life</link>
	<description>Computational Biology</description>
	<lastBuildDate>Thu, 11 Mar 2010 09:04:05 +1300</lastBuildDate>
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		<title>Comment on High speed international connection? Yes, please by Grant</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/03/11/high-speed-international-connection-yes-please/comment-page-1/#comment-5851</link>
		<dc:creator>Grant</dc:creator>
		<pubDate>Thu, 11 Mar 2010 09:04:05 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1642#comment-5851</guid>
		<description>Some technical details have been posted on the Pacific Fibre news blog:

http://blog.pacificfibre.net/uncategorized/the-technical-details/

It&#039;s interesting to note they intend to offer to sell Auckland  Wellington, effectively competing with the internal network over these two points.

Jim Nixon also has a brief post up:  http://sciblogs.co.nz/light-my-fibre/2010/03/11/pacific-fibre-undersea-cable-connection/</description>
		<content:encoded><![CDATA[<p>Some technical details have been posted on the Pacific Fibre news blog:</p>
<p><a href="http://blog.pacificfibre.net/uncategorized/the-technical-details/" rel="nofollow">http://blog.pacificfibre.net/uncategorized/the-technical-details/</a></p>
<p>It&#8217;s interesting to note they intend to offer to sell Auckland  Wellington, effectively competing with the internal network over these two points.</p>
<p>Jim Nixon also has a brief post up:  <a href="http://sciblogs.co.nz/light-my-fibre/2010/03/11/pacific-fibre-undersea-cable-connection/" rel="nofollow">http://sciblogs.co.nz/light-my-fibre/2010/03/11/pacific-fibre-undersea-cable-connection/</a></p>
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		<title>Comment on Reproducible research and computational biology by Grant Jacobs</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/01/24/reproducible-research-and-computational-biology/comment-page-1/#comment-5639</link>
		<dc:creator>Grant Jacobs</dc:creator>
		<pubDate>Thu, 11 Mar 2010 01:41:17 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1183#comment-5639</guid>
		<description>Just a loose thought: Talking about reproducibility in terms of absolutes probably may not be helpful? Some might argue that in pragmatic terms, reproducibility is by degree, how much effort is involved. (I realise this moves it to a nebulous &quot;how much is enough&quot;. I&#039;m not saying I agree with, just tossing it in.)

I think a little care is needed when pointing at one tool or another as if it&#039;s going to be a magic bullet :-) It&#039;s also a matter of &lt;i&gt;how&lt;/i&gt; you use the tools. If you ignore whatever reproducibility features they have...

With that in mind, I think no matter what tools are developed, the &quot;real&quot; problem is finding a (nice!) way to make it in academic researchers&#039; interest to do this.

Sticking my neck out a bit, I&#039;d quibble (in an academic fashion...) that standardisation is closer to what the MLs offer, or this is what I would have thought was their &quot;point of difference&quot; compared to other approaches. Consider my case example: I had reproducibility going. (Well, bits of it...) Sure it was unique to that program! No two ways about that... But it was *there*. (In the late 1980s, too! Got to give myself some credit...) One-off implementations or reproducibility features, like mine, can achieve reproducibility with respect to (that implementation of) that product. Standardisation helps wider adoption, hence the standardised MLs.

Finally, Tiwari mentions that some journals are calling for SBML/CellML for systems biology. Wouldn&#039;t this be an acknowledgement that there &lt;i&gt;is&lt;/i&gt; a problem, not that it&#039;s not an issue? (I don&#039;t work in systems biology, btw.) I can&#039;t imagine that they&#039;d see the need to ask for it otherwise. Crystallography and other areas have faced this too. Food for thought: a number of years ago, there was considerable fuss over bioinformatics journals not requiring that the software be made available &lt;i&gt;at all&lt;/i&gt; at the time of publication. 

I can&#039;t help but think that this is a general problem that continually re-surfaces. At some point in time people decide it&#039;s too much of an issue and &quot;demand&quot; that the journals (or databases) insist on additional material to resolve the issue. And then a few years later it recurs, but about some other aspect. (Note I&#039;ve shifted to a broader view that just software.) To me the underlying reason is probably the conflicts between the driving goals of academic researchers doing the work and others&#039; interests in their work.

(This has gotten long enough that perhaps I ought to resurrect it as a blog post... &lt;i&gt;sigh&lt;/i&gt;.)</description>
		<content:encoded><![CDATA[<p>Just a loose thought: Talking about reproducibility in terms of absolutes probably may not be helpful? Some might argue that in pragmatic terms, reproducibility is by degree, how much effort is involved. (I realise this moves it to a nebulous &#8220;how much is enough&#8221;. I&#8217;m not saying I agree with, just tossing it in.)</p>
<p>I think a little care is needed when pointing at one tool or another as if it&#8217;s going to be a magic bullet :-) It&#8217;s also a matter of <i>how</i> you use the tools. If you ignore whatever reproducibility features they have&#8230;</p>
<p>With that in mind, I think no matter what tools are developed, the &#8220;real&#8221; problem is finding a (nice!) way to make it in academic researchers&#8217; interest to do this.</p>
<p>Sticking my neck out a bit, I&#8217;d quibble (in an academic fashion&#8230;) that standardisation is closer to what the MLs offer, or this is what I would have thought was their &#8220;point of difference&#8221; compared to other approaches. Consider my case example: I had reproducibility going. (Well, bits of it&#8230;) Sure it was unique to that program! No two ways about that&#8230; But it was *there*. (In the late 1980s, too! Got to give myself some credit&#8230;) One-off implementations or reproducibility features, like mine, can achieve reproducibility with respect to (that implementation of) that product. Standardisation helps wider adoption, hence the standardised MLs.</p>
<p>Finally, Tiwari mentions that some journals are calling for SBML/CellML for systems biology. Wouldn&#8217;t this be an acknowledgement that there <i>is</i> a problem, not that it&#8217;s not an issue? (I don&#8217;t work in systems biology, btw.) I can&#8217;t imagine that they&#8217;d see the need to ask for it otherwise. Crystallography and other areas have faced this too. Food for thought: a number of years ago, there was considerable fuss over bioinformatics journals not requiring that the software be made available <i>at all</i> at the time of publication. </p>
<p>I can&#8217;t help but think that this is a general problem that continually re-surfaces. At some point in time people decide it&#8217;s too much of an issue and &#8220;demand&#8221; that the journals (or databases) insist on additional material to resolve the issue. And then a few years later it recurs, but about some other aspect. (Note I&#8217;ve shifted to a broader view that just software.) To me the underlying reason is probably the conflicts between the driving goals of academic researchers doing the work and others&#8217; interests in their work.</p>
<p>(This has gotten long enough that perhaps I ought to resurrect it as a blog post&#8230; <i>sigh</i>.)</p>
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		<title>Comment on Upcoming popular lectures by Professor Lawrence Krauss by Grant Jacobs</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/03/10/upcoming-popular-lectures-by-professor-lawrence-krauss/comment-page-1/#comment-5192</link>
		<dc:creator>Grant Jacobs</dc:creator>
		<pubDate>Wed, 10 Mar 2010 09:29:42 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1635#comment-5192</guid>
		<description>Jayson,

Good to hear you’ll be going to the talk. I put this up in the hope that it might attract a few people from outside the university. I think sometimes the public talks offered by the university don&#039;t reach the general public as well as they might.</description>
		<content:encoded><![CDATA[<p>Jayson,</p>
<p>Good to hear you’ll be going to the talk. I put this up in the hope that it might attract a few people from outside the university. I think sometimes the public talks offered by the university don&#8217;t reach the general public as well as they might.</p>
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		<title>Comment on Homeopathy check-up: Not in the health system, disclaimers on labels by Grant Jacobs</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/02/23/homeopathy-check-up-not-in-the-health-system-disclaimers-in-pharmacies/comment-page-1/#comment-5074</link>
		<dc:creator>Grant Jacobs</dc:creator>
		<pubDate>Wed, 10 Mar 2010 04:48:46 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1435#comment-5074</guid>
		<description>It’s come to attention that others argue that the intentions in homeopathy&#039;s founder (Hahnemann) use of the term &#039;allopathy&#039; and what is meant by modern medicine differ. If so, my explanation of the meaning of the term is wrong. Interested readers may want to read Kimball Atwood’s explanation (see the section &#039;Homeopathy vs. “Allopathy”&#039;):

http://www.sciencebasedmedicine.org/?p=21

She writes that &#039;allopathy&#039; was originally was meant as a reference to only suppressing symptoms, which is &lt;i&gt;not&lt;/i&gt; what modern medicine aims to do. She goes on to explain how even in it’s own day, the use of the term didn’t make sense (some &quot;conventional&quot; treatments of the day were aimed at the underlying cause, even if the treatments would not be considered sound today).

Kimball is pointing out a straw-man argument make by proponents of homeopathy, where through this term modern medicine is incorrectly represented as only dealing with symptoms and not the underlying causes.</description>
		<content:encoded><![CDATA[<p>It’s come to attention that others argue that the intentions in homeopathy&#8217;s founder (Hahnemann) use of the term &#8216;allopathy&#8217; and what is meant by modern medicine differ. If so, my explanation of the meaning of the term is wrong. Interested readers may want to read Kimball Atwood’s explanation (see the section &#8216;Homeopathy vs. “Allopathy”&#8217;):</p>
<p><a href="http://www.sciencebasedmedicine.org/?p=21" rel="nofollow">http://www.sciencebasedmedicine.org/?p=21</a></p>
<p>She writes that &#8216;allopathy&#8217; was originally was meant as a reference to only suppressing symptoms, which is <i>not</i> what modern medicine aims to do. She goes on to explain how even in it’s own day, the use of the term didn’t make sense (some &#8220;conventional&#8221; treatments of the day were aimed at the underlying cause, even if the treatments would not be considered sound today).</p>
<p>Kimball is pointing out a straw-man argument make by proponents of homeopathy, where through this term modern medicine is incorrectly represented as only dealing with symptoms and not the underlying causes.</p>
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		<title>Comment on Upcoming popular lectures by Professor Lawrence Krauss by Jayson</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/03/10/upcoming-popular-lectures-by-professor-lawrence-krauss/comment-page-1/#comment-4995</link>
		<dc:creator>Jayson</dc:creator>
		<pubDate>Wed, 10 Mar 2010 02:10:17 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1635#comment-4995</guid>
		<description>I will be there to listen to this interesting lecture. We don&#039;t get any good concerts or sporting fixtures in Dunedin but we can at least get some good talks thanks to the University.</description>
		<content:encoded><![CDATA[<p>I will be there to listen to this interesting lecture. We don&#8217;t get any good concerts or sporting fixtures in Dunedin but we can at least get some good talks thanks to the University.</p>
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		<title>Comment on Upcoming popular lectures by Professor Lawrence Krauss by David Winter</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/03/10/upcoming-popular-lectures-by-professor-lawrence-krauss/comment-page-1/#comment-4969</link>
		<dc:creator>David Winter</dc:creator>
		<pubDate>Wed, 10 Mar 2010 01:12:46 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1635#comment-4969</guid>
		<description>I just read this email too, can&#039;t wait!</description>
		<content:encoded><![CDATA[<p>I just read this email too, can&#8217;t wait!</p>
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		<title>Comment on Molecular biology in museums by Upcoming popular lectures by Professor Lawrence Krauss &#124; Code for Life</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/03/09/molecular-biology-in-museums/comment-page-1/#comment-4956</link>
		<dc:creator>Upcoming popular lectures by Professor Lawrence Krauss &#124; Code for Life</dc:creator>
		<pubDate>Wed, 10 Mar 2010 00:46:36 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1570#comment-4956</guid>
		<description>[...] Molecular biology in museums [...]</description>
		<content:encoded><![CDATA[<p>[...] Molecular biology in museums [...]</p>
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		<title>Comment on Sunday reading links: More on Ida, YouTube captions (again), newspaper horders, books on the iPad, swine flu by Grant Jacobs</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/03/07/sunday-reading-links-more-on-ida-youtube-captions-again-newspaper-horders-books-on-the-ipad-swine-flu/comment-page-1/#comment-4890</link>
		<dc:creator>Grant Jacobs</dc:creator>
		<pubDate>Tue, 09 Mar 2010 22:19:13 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1592#comment-4890</guid>
		<description>Those interested in the story about Ida&#039;s relationship to human origins, might also like Brian&#039;s newest article:

http://scienceblogs.com/laelaps/2010/03/at_times_the_study_of.php</description>
		<content:encoded><![CDATA[<p>Those interested in the story about Ida&#8217;s relationship to human origins, might also like Brian&#8217;s newest article:</p>
<p><a href="http://scienceblogs.com/laelaps/2010/03/at_times_the_study_of.php" rel="nofollow">http://scienceblogs.com/laelaps/2010/03/at_times_the_study_of.php</a></p>
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		<title>Comment on The inheritance of face recognition (should you blame your parents if you can&#8217;t recognise faces?) by ResearchBlogging.org News &#187; Blog Archive &#187; Editor&#8217;s Selections:</title>
		<link>http://sciblogs.co.nz/code-for-life/2010/03/03/the-inheritance-of-face-recognition/comment-page-1/#comment-4730</link>
		<dc:creator>ResearchBlogging.org News &#187; Blog Archive &#187; Editor&#8217;s Selections:</dc:creator>
		<pubDate>Tue, 09 Mar 2010 16:25:39 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=1521#comment-4730</guid>
		<description>[...] We know that some people are amazingly good at recognizing faces. How did they get that way? Code For Life examines a recent study. [...]</description>
		<content:encoded><![CDATA[<p>[...] We know that some people are amazingly good at recognizing faces. How did they get that way? Code For Life examines a recent study. [...]</p>
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		<title>Comment on Gluckman on science in small countries, part I by For success, create the conditions for creativity? &#124; Code for Life</title>
		<link>http://sciblogs.co.nz/code-for-life/2009/11/02/gluckman-on-science-in-small-countries-part-i/comment-page-1/#comment-4649</link>
		<dc:creator>For success, create the conditions for creativity? &#124; Code for Life</dc:creator>
		<pubDate>Tue, 09 Mar 2010 13:18:44 +0000</pubDate>
		<guid isPermaLink="false">http://sciblogs.co.nz/code-for-life/?p=425#comment-4649</guid>
		<description>[...] Gluckman on science in small countries, part I [...]</description>
		<content:encoded><![CDATA[<p>[...] Gluckman on science in small countries, part I [...]</p>
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