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Posts Tagged anti-vaccine

Martin Raff on what is autism Grant Jacobs May 31

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The open-access scientific journal BMC Biology is currently hosting an interview with Martin Raff, presenting his responses to questions about autism. Prof. Raff gives the background in simple form well.

A neurobiologist with an excellent scientific pedigree Professor Raff did not study autism during his research career, but became interested in it after he retired when his grandson was found to be autistic.

BMC Biology has placed a copy of their interview in two parts on YouTube™, which I have included below. A transcript of the interviews can be found on the BMC website for those that prefer to read it rather than listen. There are references to further reading at the end of the transcript.

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Brevia – Wakefield saga continues… struck off Grant Jacobs May 24

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Andrew Wakefield, the doctor behind the MMR-vaccine scare, has been struck off by the UK’s General Medical Council. While this forbids him from practicing in the UK, he has lived in the USA for the last several years. (Reports say that the ruling does not affect his ability to practice medicine outside the UK.) He previously resigned (or was removed) from his position in Thoughtful House in the USA and has had his controversial research paper retracted, with another withdrawn. The Times Online has a timeline of events spanning over the 12 years of this on-going story.

As others point out, this is unlikely to be the last we will hear from or of him. Latest reports include media interviews and him providing the ‘keynote’ speech for anti-vaccine rally.


Previous articles on Code for life on the Wakefield saga:

Has Andrew Wakefield resigned from Thoughtful House? (Updated)

Another Wakefield paper pulled?

Lancet formally retracts Wakesfield paper


Has Andrew Wakefield resigned from Thoughtful House? (Updated) Grant Jacobs Feb 18

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Andrew Wakefield, whose work has been at the heart of a MMR vaccine “scare”, has been in the news of late owing to the UK General Medical Council ruling on his 1998 Lancet paper, the retraction of this research paper and more recently the withdrawal of another research paper.

Orac has a blog post tonight querying if this news of his resignation is true. If it’s true, and I want to stress that “if”, it’s a bit of a bolt out of the blue. At the moment there is no formal announcement on the Thoughtful House website.

Thoughtful House’s response to the GMC ruling was very much to support Wakefield, so this would be a considerable shift in position. [This web page has now been removed, see update below.]

While still awaiting confirmation Brian Deer, the investigative journalist behind bringing this story to the public eye, has just commented:

Yes, I heard this was coming some days ago.

With this in hand, I would say we should be looking forward to a formal confirmation of this news in the near future. (I trust no-one is silly enough to be posing as Brian Deer!)

Update: [7:30am 19-Feb-2010] While no formal statement of Wakefield resignation has been posted, Thoughtful House has removed their statement responding to the GMC ruling and have removed Wakefield from the list of staff on their website.


Other posts on Wakefield and autism on Code for life:

Another Wakefield paper pulled?

Lancet formally retracts Wakesfield paper

Autistic children and blood mercury levels

Another Wakefield paper pulled? Grant Jacobs Feb 13

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In recent news the Lancet article by Andrew Wakefield that, in part, lay behind the MMR vaccination scare in the UK and elsewhere was retracted subsequent to a ruling by the UK General Medical Council’s Fitness to Practise Panel. (‘In part’ because mainstream media reportage and Wakefield’s statements to the media and public also played a role—arguably the larger role—in creating the scare.)

(Source: wikipedia)

(Source: wikipedia)

The latest news is that Neurotoxicity has withdrawn a recent paper titled Delayed acquisition of neonatal reflexes in newborn primates receiving a thimerosal-containing Hepatitis B vaccine: Influence of gestational age and birth weight in which Andrew Wakefield is the senior author.

Details as to the reason behind the withdrawal are not yet available to the best of my knowledge.

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Rubella, not a benign disease if experienced during early pregnancy Grant Jacobs Feb 10

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The MMR vaccine is targeted at measles, mumps and rubella. The latter, rubella, is a cause of abortions and developmental defects in children of mothers who are infected with the virus during the first twenty weeks of pregnancy.

Cataracts

Cataracts in a CRS infant (Source: wikipedia.)

It is sometimes useful to look at historical papers to get a perspective of present-day issues. An advantage is that you can look at work written prior to current fuss, such as the anti-vaccine noise over the MMR vaccine over the past ten or so years, which Andrew Wakefield’s now retracted research article plays a central but by no means exclusive role.1

The rubella component of the MMR vaccine is targeted to mothers to counter infection during their first two trimesters of pregnancy.

Infection during the first trimester results in about a half of the infants being affected, falling to about one-quarter when infection occurs during the second trimester, with few effects observed for infection occurring after 20 weeks.

“Rubella kids”, like myself, have what is called congenital rubella syndrome (CRS), having one or more of three common symptoms:

  • Slightly more than one-half of CRS infants have sensorineural deafness
  • Somewhat less than one-half have eye abnormalities of various kinds, particularly cataracts (see illustration above) and microphthalmia (small eyes).
  • Heart defects occur in approximately one-half of CRS infants.2

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Lancet formally retracts Wakesfield paper Grant Jacobs Feb 03

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Heading the home page of medical journal The Lancet is an announcement of the formal retraction of the Wakefield paper that in part sparked the MMR vaccination scare in the UK and elsewhere. (I write ‘in part’ as other factors, such as Wakesfield’s public addresses and uncritical media coverage have their role in the saga.)

The retraction statement reads:

Following the judgment of the UK General Medical Council’s Fitness to Practise Panel on Jan 28, 2010, it has become clear that several elements of the 1998 paper by Wakefield et al are incorrect, contrary to the findings of an earlier investigation. In particular, the claims in the original paper that children were “consecutively referred” and that investigations were “approved” by the local ethics committee have been proven to be false. Therefore we fully retract this paper from the published [record.]

Scibling Peter Giffin’s article from earlier this week reports on the findings of the UK’s General Medical Council with respect to Wakesfield’s work. I’ve earlier written about autism and it’s proported links to vaccination.

Addendum: Also worth reading for some wider context are any number of articles about autism and parent’s hopes of a “treatment”, like this article by Liane Carter in the New York Times.

Update (19-Feb-2010): It would seem that Wakefield has resigned from Thoughtful House.

Monday potpourri: maps, malaria in the USA, cholera in Dunedin and vaccines Grant Jacobs Dec 07

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A collection of interesting titbits to lighten up a mundane Monday evening…

Malaria in Eastern USA in 1870 (Source Library of Congress digital maps collection, via Mystery Rays from Outer Space)

Malaria in Eastern USA in 1870 (Source Library of Congress digital history collection, via Mystery Rays from Outer Space)

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What comedian and vaccine critic Bill Mayer wrote Grant Jacobs Nov 17

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It might even be funny if Maher weren’t serious.

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Autistic children and blood mercury levels Grant Jacobs Oct 27

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Autism has received great attention over the past couple of decades, from movies like Rain Man to the fuss stirred up by anti-vaccine promoters who insist that “mercury” (thimerosal) in vaccines causes autism.

If you’ve ridden the waves of the autism-related anti-vaccine silliness on the WWW you’ll appreciate research that tries bring back a positive focus on what causes autism. Of course, part of that is trying to convince those promoting the notion that mercury causes autism to (please) stop.

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