Michael Knapp

The discovery of a Denisovan jaw bone and what it can tell us - Guest Work

May 09, 2019

Last week the discovery of a lower jaw bone of a Denisovan hit the headlines all over the world. Denisovans are a now-extinct species of humans that were closely related to us as well as to Neanderthals. To an outside observer, the excitement of researchers about this find might have appeared a bit over the top. After all, Denisovans have been discovered nearly 10 years ago, their genome has been sequenced and their relationship to our own species analysed. So, what is all this fuss about? The jawbone was found in Baishiya Karst Cave, on the Tibetan Plateau, in 1980 by a monk. Supplied/Dongju Zhang, Lanzhou University The relatively large amount of recent, high-profile research on Denisovans means that they have become a rather well-known entity in our family tree, if not a household name like Neanderthals. This familiarity … Read More

New Zealand, the place that makes giant birds - Guest Work

Mar 20, 2019

Fourteen years ago, I was a PhD student somewhere half-way through my degree and had just published my first paper. As I proudly flicked through the hard copy of the journal, I noticed another article that caught my interest. Using DNA extracted from ancient bones, an international team lead by researchers from Oxford University and Palaecol Research in Christchurch had managed to reconstruct the DNA sequence of a small fragment of the legendary Haast’s eagle’s mitochondrial genome. With a weight of approximately 15 kg and a wingspan of close to three meters, the extinct New Zealand Haast’s eagle is the largest known eagle to have ever lived. By comparing the Haast’s eagle’s DNA fragment to the same fragment from other eagles, the authors had expected to confirm that the New Zealand giant was a remote cousin of the … Read More

TB or not TB: origin and antiquity of tuberculosis in New Zealand - Guest Work

Oct 25, 2018

Recently, our team at the University of Otago embarked on a quest to identify how and when Tuberculosis (TB) reached New Zealand, by looking for the genetic signature of Tuberculosis bacteria in ancient human and animal remains from across the country. Tuberculosis is a bacterial disease which has been called a “global health emergency” by the World Health Organization, killing 1.7 million people a year. Despite being treatable, it has surpassed HIV/AIDS as the most deadly infectious disease on the planet. So, clearly, it is a major health problem around the world, including New Zealand. But why should we care how and when TB arrived in New Zealand? It is here now, so shouldn’t we spend all available resources into research directly leading to better treatment and prevention? Let’s compare the situation with a street brawl. If you are unexpectedly … Read More