I think this clip from Symphony of Science identifies one of the things that motivates scientists – pushing our existing knowledge to (and beyond) the edge of what is known. And it is just as relevant to chemistry, biology, physics or psychology, as it is for astronomy or astrophysics.
In chemistry, we push beyond the edge by discovering and creating new materials which open further opportunities in terms of new technologies and concepts. Also, there is a drive to doing this in a more environmentally friendly way. I’m sure others can highlight how they think their fields push beyond “the edge” of what is known better than I can.