Tagged: bioinformatics

Data parasites eh? - Code for life

Grant Jacobs Jan 24, 2016

Apparently researchers who use other’s data without collaborating with them are ‘research parasites’, according to an editorial from the New England Journal of Medicine. This has caused quite a fuss, with some expressing their opinion on the twitter streams #dataparasites and #researchparasites. I think the editorial conflates data sharing with other issues. Data sharing is an important part of science, but … Read More

What does a chromosome look like? (Not Just DNA #2) - Code for life

Grant Jacobs Nov 14, 2013

Aside from the fun of peering at the stuff that codes for the parts that make up us, knowing how a chromosome is arranged inside a cell nucleus might tell us a lot about how our genes work. Understanding the structures of genomes might well be what is needed to make sense of the genetics of complex diseases. Read More

Computer modellers for the win - Code for life

Grant Jacobs Oct 10, 2013

As a computational biologist I rather like the look of this year’s Nobel Prize for Chemistry - it’s been awarded for contributions to computational modelling, to Martin Karplus (University de Strasbourg/Harvard), Michael Levitt (Standford) and Arieh Warshel (University of Southern California). Molecular modelling takes several forms. The twist in the work the prize … Read More

Alternative bioinformatics - Code for life

Grant Jacobs Jul 04, 2013

There’s alternative ‘medicine’, then there’s alternative bioinformatics. Those who aren’t computational biologists / bioinformaticists should proceed no further. You really won’t get these, they’re way too in-house. You really need do to know something of the tools to make sense of them. But that’s also the beauty of it. I’ve just selected a … Read More

More winning science reading - Code for life

Grant Jacobs May 15, 2013

I’d like to return to writing ‘proper’ posts, both for general readers and scientists. But there’s a lack of this thing called free time—I think it’s called that, I’ve forgotten—that’s getting in the way. Readers could try the winners of the inaugural Science Seeker Awards. Don’t ask me how 3 judges whittle down over 350 entries to … Read More

Nature’s reproducibility effort: when to get data specialists on board - Code for life

Grant Jacobs Apr 27, 2013

Scientific magazine Nature has announced an initiative to aimed at aiding the reproducibility of biological research papers. They’re planning to expand the methods section to cater for this, introducing a checklist and offering a Protocol Exchange site. I’d like to draw attention to one point ArsTechnica’s coverage of this development noted that has wider … Read More

Epigenetic dynamics – free - Code for life

Grant Jacobs Mar 15, 2013

Those with interests in epigenetics and genome structure may want to check out Nature Structural and Molecular Biology’s focus on epigenetic dynamics. (This gives me an opportunity to briefly sound off on a favourite topic…) One fascinating development over the past few years has been explorations of the three-dimensional nature of genomes, how they are … Read More

Structured procrastination, 2 Dec 2012 - Code for life

Grant Jacobs Dec 03, 2012

Another edition of my irregular structured procrastination reading lists - have fun exploring these. (Geekier ones nearer the end.) Sci-fi movie Geneticist Ricki Lewis offers a review of Jim, which she says is more compelling than GATTACA. The movie can be viewed on-line. (If you watch it, let me know what you think.) … Read More