Tagged: DNA sequencing

A long read, and a tricky jigsaw puzzle - Genomics Aotearoa

Genomics Aotearoa Apr 05, 2019

Peter Dearden Sequencing is an essential part of creating a genome, be it human, stick insect, kākāpō or sheep (all genomes Genomics Aotearoa is currently working on). But what is sequencing, how does it work, and why does it take so long?  And why does it matter to us? Sequencing is a laboratory process where segments of DNA base pairs … Read More

Frederick Sanger 1918-2013 Chemist who pioneered protein and DNA sequencing - Code for life

Grant Jacobs Nov 21, 2013

Two-time Nobel Prize winner and pioneer of techniques that brought on modern biology, Frederick Sanger, died yesterday, aged 95. His DNA and protein sequencing techniques are early steps to the world of high-speed DNA sequencing we have today, with whole genomes reported frequently and diagnosis of genetic components of disease, to mention just two applications. Knowing the … Read More

Boney lumps, linkage analysis and whole genome sequencing - Code for life

Grant Jacobs Jul 06, 2010

We all have our lumps, the quirky features we develop with time. Some of these are bone spurs, extra growths of bone. These can be caused from damage to joints, like the lumpy joints seen in elderly people with arthritis. Bone spurs from differing causes can develop in many parts of the body, spine, … Read More

Myriad Genetics patent of BRCA (breast cancer) genes denied - Code for life

Grant Jacobs Mar 30, 2010

Myriad Genetics face a judicial ruling against their patent of the BRAC1 and BRAC2 genes. Solution structure ensemble of BRCA1/BARD1 RING domain heterodimer. Brzovic, Rajagopal, Hoyt, King and Klevit Nat. Struct. Biol. 8:833 (2001) (Source: PDB.) Judge Sweet presented this as to centre around the issue, Are isolated human genes and the comparison of their … Read More

Molecular biology in museums - Code for life

Grant Jacobs Mar 09, 2010

The past fifty years has seen the rise of molecular biology. Many museums have little to represent molecular biology and it’s impact on medicine, perhaps because the objects studied in molecular biology are usually visualised indirectly, whereas museum visitors traditionally go to view objects with their own eyes. [caption id="attachment_1573" align="alignright" width="350"] Canterbury Museum, Christchurch, New Zealand. Note … Read More

Next Generation Sequencing workshop - Code for life

Grant Jacobs Dec 15, 2009

Otago University’s sequencing facility will be hosting a two-day workshop, The Researchers Guide to Next Generation Sequencing, February 11-12th 2010. Places are limited to 20 and cost only $NZ100. Applications close 7th January. Be in quick! More details about how to apply for the workshop on their website or their flyer (below). The flyer may … Read More

  • 1
  • 2