Tagged: gene therapy

Gene Therapy and The Breakthrough Myth - Guest Work

Guest Author May 25, 2018

Becky Turner When we think of scientific advancement, Hollywood has taught us to envisage the obsessed scientist working alone in the lab late at night, hunched over a microscope or painstakingly pipetting chemicals into test tubes. Suddenly, one of the tubes turns green and starts fizzing and he’s got his breakthrough formula made. Scientists lovingly call … Read More

Solution to 50-year-old mystery could lead to gene therapy for common blood disorders - News

Jean Balchin Apr 06, 2018

In a recent study published in the journal Nature Genetics, UNSW Sydney-led researchers have used CRISPR-gene editing to introduce beneficial natural mutations into blood cells to boost their production of foetal haemoglobin. This study solves a 50-year-old mystery about how these mutations operate and alter the expression of human genes. Naturally carried by a small percentage of people, these mutations contribute to … Read More

Regulating GMOs: time to move forward - Code for life

Grant Jacobs Nov 23, 2017

It’s time to move regulation of genetic modification forward. The current set-up is temporary and unsound. We use a risk-based approach for almost everything because that’s what makes sense. But New Zealand takes an arbitrary approach to genetic modification. So we ‘ban’ a technique that evidence shows there is no special risk in using. That poor logic plays to a vocal … Read More

Public opinion of gene editing and enhancement - Code for life

Grant Jacobs Nov 21, 2017

What if we could fix a kid’s genetic disease, cure them for their lifetime? What if we make that for all of their children, forever? Or enhance humans to be genetically better? What’s your opinion of gene editing and enhancement? A survey asked what people thought. Participants gave a green light for adult gene therapy. They were cautious … Read More

USA team editing embryos, early thoughts on alternatives and limitations - Code for life

Grant Jacobs Aug 03, 2017

Widely reported today is the research paper by an USA team who edited a gene that causes sudden heart failure in young adults. I’d like to take a different approach, briefly raising just two things that nagged at me while reading this work. Before I do be clear there are real technical advances reported.* I’m not denying or opposing them. Read More

Fixing our genes - Code for life

Grant Jacobs Jul 30, 2017

Gene editing could be a big deal. It offers some great stuff. For a few applications it also raises some interesting ethical questions. We might be able to treat some genetic disorders by convert a “broken” gene associated back to the working version of the gene, potentially providing a one-time, life-long fix for the patient. Gene therapy has a surprisingly … Read More

The next frontier in reproductive tourism? Genetic modification - Guest Work

Guest Author Nov 22, 2016

Rosa Castro, Duke University The birth of the first baby born using a technique called mitochondrial replacement, which uses DNA from three people to “correct” an inherited genetic mutation, was announced on Sept. 27. Mitochondrial replacement or donation allows women who carry mitochondrial diseases to avoid passing them on to their child. These diseases can range from … Read More