Tagged: genomics

Epigenetic dynamics – free - Code for life

Grant Jacobs Mar 15, 2013

Those with interests in epigenetics and genome structure may want to check out Nature Structural and Molecular Biology’s focus on epigenetic dynamics. (This gives me an opportunity to briefly sound off on a favourite topic…) One fascinating development over the past few years has been explorations of the three-dimensional nature of genomes, how they are … Read More

Whole genome sequencing for serious vaccine complaints? - Code for life

Grant Jacobs Nov 30, 2012

While I work on longer pieces, a stray thought: how far away are we from genome screening for (court) inquiries about ‘vaccine damage’ so that those with genetic causes might be resolved promptly? A number of countries maintain databases of reports of possible adverse reactions to medications. For possible vaccine reactions, in New Zealand we have … Read More

Sea stars and mosaics - Code for life

Grant Jacobs Nov 29, 2012

At first you wonder if this sea star is real. It looks more like a kid’s geometric doodle from a distracted afternoon at school than an animal.[1] [caption id="attachment_10195" align="aligncenter" width="640"] Click on image for source; Creative Commons Attribution-Noncommercial-Share Alike 3.0 license[/caption] The World Asteriodea Database indicates Iconaster longimanus was first described in 1859. (The … Read More

All together now: high-throughput sequence mapping tool compendium - Code for life

Grant Jacobs Oct 16, 2012

Biologists and bioinformatics people interested in high-throughput (HTS) mapping may find this this one-page summary of all currently-available HTS mapping tools useful. The comparison table of the different features of each mapping tools will certainly beat having to dig this information out of the papers or on-line documentation. There’s also a timeline of when the methods first appeared. DNA, RNA, miRNA … Read More

Epigenetics overview (video) - Code for life

Grant Jacobs Apr 11, 2012

Below Jessica Tyler, from the University of Texas MD Anderson Cancer Center, introduces epigenetics, a topic I’ve touched on a few times and would like to elaborate further on. Her introduction is fairly gentle; hopefully some of the essence of the thing will come across to non-specialists! [vimeo width=”600″ height=”450″]http://vimeo.com/39781892[/vimeo] You may need to wait until … Read More

George Church on genomics and personalised medicine - Code for life

Grant Jacobs Apr 06, 2012

Weekend video - for general readers. This TEDxCambridge lecture by Professor George Church* offers an informal look at progress in genomics and personalised medicine. While very informal compared to some TED lectures, but it does give glimpses of where genomics and personalised medicine might be headed in a series of quick snapshots.** … Read More