Tagged: mice

A gene drive in mice – but only for females - Code for life

Grant Jacobs Jan 24, 2019

What if you could change a gene in a population by introducing laboratory-prepared animals then just letting nature take it’s course? A gene drive is the informal name given to a process where a genetic variation is set up so that it will be inherited more often in the offspring than it would by chance.[1] In a gene drive each generation … Read More

How rejuvenation of stem cells could lead to healthier aging - Guest Work

Guest Author Jan 25, 2018

Elisa Lazzari, Cornell University Elisa Lazzari, Postdoctoral Associate in Biomedical Sciences, Cornell University “Rampant” and “elderly” are words rarely used in the same sentence, unless we are talking of the percentage of people over 65 years old worldwide. Life expectancy has considerably increased, but it is still unknown how many of those years are going … Read More

Gene drives could wipe out island pest populations – study - News

John Kerr Aug 10, 2017

An entire island population of invasive mice could be eradicated by the single release of 100 engineered mice carrying ‘gene drives’ which spread infertility throughout a population. The finding comes from a new study which used computer simulations to investigate how gene drives – essentially sets of ‘selfish genes’ which are more likely to pass on to the next … Read More

How does the hypothalamus control ageing? - Guest Work

Guest Author Jul 28, 2017

Richard Faragher, University of Brighton If you are reading this and you don’t smoke, then your major risk factor for dying is probably your age. That’s because we have nearly eliminated mortality in early life, thanks to advances in science and engineering. But despite this progress, we still haven’t worked out how to eliminate the damaging effects … Read More

Mice lacking a sense of smell stay thin - News

Jean Balchin Jul 06, 2017

Mice that have been engineered to lack a sense of smell lose weight on a high-fat diet, according to a report in today’s issue of Cell Metabolism. The mice ate just as much as counterparts with unaltered senses, yet lost an average of about 16 percent of their body weight. This weight loss was almost entirely from … Read More

Are 300 animals a day really tortured for scientific research in New Zealand? Part II - Infectious Thoughts

Siouxsie Wiles Feb 29, 2016

In the spirit of openness and transparency, I want to share what 42 animals that were involved in my 2014 research efforts experienced. I recently blogged about Paul Henry’s interview with NZ Anti-Vivisection Society (NZAVS) executive director Stephen Mason, in which Paul Henry repeatedly referred to the 300 animals a day tortured to death in the name of … Read More

Setting sail for the Subantarctics - Field Work

Sarah-Jane O'Connor Feb 22, 2016

Update: The HMNZS Canterbury is being deployed to the Pacific to help Fiji in the recovery from Cyclone Winston. At this stage, Operation Endurance is suspended. Feb 24, 2016. It’s not every day you get a phone call asking if you’d like to jump on a boat for a few weeks and travel to a part of New … Read More

Monday Micro – artificial sweeteners & a dose of bad science - Infectious Thoughts

Siouxsie Wiles Sep 22, 2014

“Sugarcubes” by Pallbo – Own work. Licensed under Public domain via Wikimedia Commons. There has been quite a bit of coverage of a recent Nature paper reporting a link between artificial sweeteners and high blood glucose levels (1) – an important finding if true, as high blood glucose levels are … Read More

Male researchers scare the sh*t out of laboratory mice! - Infectious Thoughts

Siouxsie Wiles Apr 30, 2014

According to this press release, researchers at McGill University in Montreal have discovered that the presence of a male researcher (or even his worn t-shirt) stresses laboratory mice and rats, the equivalent to making them swim for 3 minutes or restraining them in a tube for 15 minutes. The research has just been published in the … Read More

Could dad’s-to-be drinking cause foetal abnormalities? - Infectious Thoughts

Siouxsie Wiles Feb 19, 2014

“Until now fathers’ lifestyle choices have not seen any repercussion on their unborn children. This ground-breaking research provides the first definitive evidence that fathers’ drinking habits pre-conception can cause significant fetal abnormalities.” That was from a press release for a paper in a little known journal called Animals, Cells and Systems. The foetal abnormalities they are referring to are … Read More

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